ABSTRACT
The world is facing one of its largest Pandemics ever, “The COVID-19”! The giant leaps taken in medicine and research have bowed down before a teeny tiny virus. This has conveyed to mankind that the armamentariums we possess against viruses are futile. Most of the drugs provide symptomatic relief only with few unswervingly being able to destroy the virus. Nonetheless, the scientific community is on the overtime for new boulevards of research and ways to defeat this threat. Biosurfactants (BSs) were stumbled upon as a plausible gold mine! In fact, its antimicrobial and antiadhesive properties have been well accepted. It is now postulated to be of aid in preventing the spread of viruses, that is, as a disinfecting agent, as an antiviral by curing symptoms occurring in the incubation period, killing directly the virus-infected cells and also as a drug delivery system. This chapter aims to provide an insight into what BSs are and their enormous potentials in dealing with Respiratory viruses especially the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). © 2022 Elsevier Inc. All rights reserved.